Other androgenic side effects, such as weight gain, pattern hair loss, and voice deepening, were also reported in some trials, but were excluded from analyses due to insufficient data. The United States Food and Drug Administration (FDA) stated in 2015 that neither the benefits nor the safety of testosterone supplement have been established for low testosterone levels due to aging. They recommend yearly evaluation regarding possible improvement and, if none, to discontinue testosterone; physicians should consider intramuscular treatments, rather than transdermal treatments, due to costs and since the effectiveness and harm of either method is similar. A 2020 guideline from the American College of Physicians supports the discussion of testosterone in adult men with age-related low levels of testosterone who have sexual dysfunction. Serious side effects may include liver toxicity, heart disease, and behavioral changes. You can ask your healthcare provider or pharmacist for information about Striant that is written for health professionals. If you would like more information, talk with your healthcare provider. For more information, ask your healthcare provider or pharmacist. These are not all the possible side effects of Striant. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. Keep a list of them and show it to your healthcare provider and pharmacist when you get a new medicine. The recommended dose of the nasal formulation of testosterone is 11 mg daily. Do not take two doses of testosterone at the same time. This medication is available in an injectable form to be given directly into a muscle (IM) by a healthcare professional. Striant is a steroid sex hormone indicated to treat primary hypogonadism and hypogonadotropic hypogonadism. Regularly inspect the gum area where the Striant buccal system is applied. Misuse of testosterone can cause dangerous or irreversible effects. Striant is used to treat men with low testosterone levels. Talk with your healthcare provider as soon as possible if you feel like you’re dependent on anabolic steroids. Anabolic steroids are powerful medications that affect your hormone levels and body composition. In the case of overdose with an injectable product, patients may present with a cerebrovascular event. Data regarding an overdose with a topical testosterone product is not readily available. Striant is indicated to treat primary hypogonadism and hypogonadotropic hypogonadism. Testosterone is 40% bound to sex hormone binding globulin, 2% unbound, and the remainder is bound to albumin and other proteins. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. A similar 2012 review also found increased exercise capacity and reasoned the benefits generlizable to women. A 2009 review found that testosterone had an antidepressant effect in men with depression, especially those with hypogonadism, HIV/AIDS, and in the elderly. As of 2014update, a number of lawsuits are underway against manufacturers of testosterone, alleging a significantly increased rate of stroke and heart attack in elderly men who use testosterone supplementation.needs update Major brand names of testosterone and/or its esters include Andriol, Androderm, AndroGel, Axiron, Delatestryl, Depo-Testosterone, Intrinsa, Nebido, Omnadren, Primoteston, Sustanon, Testim, TestoGel, TestoPatch, Testoviron, and Tostran. Shortly thereafter, in 1937, testosterone first became commercially available as a pharmaceutical drug in the form of pellets and then in ester form for intramuscular injection as the relatively short-acting testosterone propionate.